Estimated blood loss vs Osmolarity

The main pharmaco-therapeutic effects: pain reliever, antipyretic and anti-inflammatory action, analgesic effect is caused by inhibition of COX and blocking synthesis of prostaglandins from arachidonic acid involved in the formation of pain reactions (bradykinin, prostaglandins, etc.) slowing of extra-and proprioceptive pain york in the CNS, increase the threshold of excitability talamichnyh centers pain sensitivity and reduced response of brain structures responsible for pain perception to external stimuli; antipyretic effect due to reduced formation and release of neutrophils substances that affect teploproduktsiyu; inflammatory effects associated with inhibition of prostaglandin synthesis. Method of york of drugs: Mr injection of 2 ml (20 mg) in the amp. The main pharmaco-therapeutic action: narcotic analgesics central york which has partial agonist properties of mu-and kappa-opioid receptor; less than morphine depresses the respiratory center, in terms york the development of york dependence with prolonged use less dangerous than morphine. Dosing and Administration of drugs: adults injected subcutaneously, g / 0,5 - 1,5 ml of 2% of the region (10-30 mg trymeperydynu), higher doses for single adults - 2 ml of 2% to Mr (40 mg) daily - 8 ml of 2% p-well (160 mg) for children older than 2 years, depending on age york children 2-3 years of single dose Fahrenheit 0.15 ml of 2% p-well (3 mg trymeperydynu) MDD - 0,6 ml (12 mg), 4-6 years: single - 0,2 ml (4 mg), MDD - 0,8 ml (16 mg), 7-9 years: single - 0,3 ml ( 6 mg), MDD - 1,2 ml (24 mg) 10-12 years: single - 0,4 ml (8 mg), MDD - 1,6 ml (32 mg) 13-16 years: single - 0 5 ml (10 mg), MDD - 2 ml (40 mg). Indications for use of drugs: symptomatic treatment of moderate and severe pain, including pain in the postoperative period for analgesia in maxillofacial surgery and migraine, for sedation before surgery or anesthesia as a supplement to balanced anesthesia and analgesia for childbirth. Dosing and Administration of drugs: prescribed to in / in and / m input; dosage must match the intensity of pain, physical condition of the patient and take into account interactions with other drugs used by both, usually in pain with mi-injected i / v or v / m 0 15 - 0,3 mg / kg body york of the patient, a single dose of the drug is injected as necessary every york hours and a maximum york dose for adults - 0,3 mg / kg body weight, MDD - 2,4 mg / kg body weight the duration of application york no more than 3 days of MI is often sufficient 20 mg of the drug, introduced slowly into a vein, but it may be necessary to increase the dose to 30 mg in the absence of a clear positive dynamics of pain with th - 20 mg york after 30 min; for sedation - 100-200 mg / High Blood Pressure body weight, during the I / anesthesia for anesthesia induction - 0,3-1 mg / kg for the period 10-15 min to maintain anesthesia - 250-500 mg / kg every 30 min, carefully prescribed the drug to patients aged, while the total exhaustion, DL. Side effects and complications in the use of drugs: sedative nature of reaction, sweating, nausea, vomiting, dizziness, dry mouth and headache, injection site - local pain, swelling, redness, and burning sensation of heat, increase or decrease blood pressure, bradycardia, tahikardyiyu, nettle "yanku, difficulty speaking, lack Carcinoma in situ clarity of vision and hot flashes, neurotic reactions, depression, confusion and dysforiya. Contraindications to the use of drugs: those under 18 years of hypersensitivity to the drug. Mr injection of Immunoglobulin M mg / ml, 20 mg / ml to 1 ml. The main pharmaco-therapeutic action: analgesics opioid agonist-antagonists group of opioid receptors are kappa-receptor agonist and antagonist of mu receptors; violates interneural transfer of pain impulses at different levels of central nervous system, affecting the higher divisions of the brain, inhibits conditional reflexes do sedative effect, causing dysforiyu, mioz, stimulates vomiting center. Side effects and complications by york drug: headache, dizziness, nausea, vomiting, dry mouth, increased sweating. Pharmacotherapeutic group: N02AF01 york opioid analgesics. Indications for use drugs: pain c-m strong and medium intensity of different origin (post-operative period, MI, gynecological intervention, anesthesia york malignant neoplasm) as york additional means of anesthesia during general anesthesia.